Columbia University Bio Bytes

Columbia University Bio Bytes

Columbia Sys Bio Initiative

Welcome to Bio Bytes, your starting point for all things Systems Biology. Tune in for interviews with prominent scientists working at the intersection of Biology, Engineering, Medicine, Computer Science, and Mathematics. If you're interested in other ways in which biology and biomedicine are impacting the world, check out our sister podcast "BioWorks" ( for great discussions on life science-related business, investing, and policy. Please email with any inquiries about Bio Bytes. Logo credit: Vivian Shi (

Categorias: Ciencia y Medicina

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In which Neil Vasan, assistant professor of medicine and medical oncologist at the Columbia University Irving Medical Center, and Vaibhav discuss the biochemistry and structural biology of kinases, as well as their salience in cancer development and progression. Neil tells the story behind his critical discovery of hyper-activating double mutations cooccurring in cis on PI3K alleles, discusses his group's use of deep mutational scanning in elucidating mechanisms of drug resistance and disease pathogenesis, and describes his efforts to illuminate the dark phosphoproteome. As well, he discusses how proteomics complements genomic approaches to understanding cancer and provides advice for aspiring physician-scientists. 

Episodios anteriores

  • 31 - Bio Bytes 29: Kinase Proteomics and Oncology with Neil Vasan 
    Thu, 28 Apr 2022
  • 30 - Bio Bytes 28: Systems Approaches to Studying Neural Circuitry with Darcy Kelley  
    Sun, 13 Mar 2022
  • 29 - [Bioworks 3]: Biotech Incubators and the Fourth Purpose Task Force with Sam Sia 
    Fri, 18 Feb 2022
  • 28 - Bio Bytes 27: Microbial Systems and Synthetic Biology with Harris Wang 
    Fri, 19 Nov 2021
  • 27 - Bio Bytes 26: Precision Medicine with Adam Bass 
    Sun, 07 Nov 2021
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